January/February 2002
Volume Two - Issue One

Winners Announced for 2001 Steven J. Fenves Awards

ICES to Administer Dowd Engineering Fund

PITA Fiscal Year 2002 Awards

Update: ICES Strategic Plan

New Card Reader System in Hamburg Hall

Genesis Baby Drive

Rhonda Moyer receives Burritt Education Award

Raj Sinha receives PhD

Art Westerberg elected Distinguished Professor of Engineering

Helen Granger Becomes Freelancer

 

ICES Calendar

Annual ICES Holiday Party

ICES Seminars

PITA Symposium 2002

 

Nanoscale Heat-Transfer Project

Biomedical Engineering at ICES

Asim Smailagic

Kacey Marra

Christian Buergy

Printable iNews

iNews homepage

iNews Archives

ICES homepage

Carnegie Mellon Engineering homepage

Carnegie Mellon University homepage

 


NEWS & ANNOUNCEMENTS

WINNERS ANNOUNCED FOR 2001 STEVEN J. FENVES AWARD

Professor Ulrich Flemming*, Architecture, and Chris Hendrickson*, Civil & Environmental Engineering, professor and department head, are the recipients of the 2001 Steven J. Fenves Award for Systems Research. This award is presented each year to one or more individuals within Carnegie Mellon who have made significant contributions to systems research in areas relevant to ICES. Congratulations to both recipients for their outstanding careers and for their many and lasting contributions to the Institute for Complex Engineered Systems and Carnegie Mellon.

Ulrich Flemming has contributed pioneering work on the development and demonstration of integrated engineering/architecture design systems and its influence on subsequent EDRC research and on a large number of EDRC graduates now pursuing engineering design research and education elsewhere. Moreover, he has intertwined the professions of engineering and architecture. He has developed knowledge-based approaches to capture design knowledge and to integrate it into generative design systems. Issues in case-based design, design interfaces; human-computer interaction; design databases and application integration have recently become a sought after focus. Congratulations Ulrich.

Chris Hendrickson has made pioneering contributions to systems research in engineering planning and management, including design for the environment, and project management and for contributions as education director of the EDRC and support for ICES. Chris has concentrated lately on green design, exploring the environmental life cycle consequences of alternative product and process designs. He has contributed software tools and methods for pollution prevention and environmental management in addition to including life cycle analysis software and a widely cited analysis of the life cycle consequences of lead acid battery powered vehicles. In addition to all his scholar and civic contributions, Chris led the very successful undergraduate engineering curriculum reform at Carnegie Mellon in 1989/90. Congratulations Chris.


ICES TO ADMINISTER DOWD ENGINEERING SEED FUND
The Philip and Marsha Dowd Engineering Seed Fund (Dowd Fund) was established in 2001 through a generous $463,800 gift to the College of Engineering (CIT) from the Dowds. Annual proceeds from the fund will be used to provide a fellowship grant to a CIT graduate student.

The fellowship grant program is administered through ICES under the oversight of the grant selection committee. Fellowship grants will be awarded to CIT graduate students in the second or third year of the PhD program. CIT Faculty may submit proposals for support from this program to the Director of ICES. Proposals must describe the research/dissertation project that the student will work on (two pages maximum) and include a one page Curriculum Vitae of the student.

The Director of ICES shall announce a Call for Proposals during February of each year. Proposals must be submitted by April 1 each year. ICES will review the proposals and select four of them for final consideration by the grant selection committee. The grant selection committee shall include the following members: the Director of ICES, the Dean of CIT and Mr. and Mrs. Dowd. The committee will consider the following criteria when evaluating the final proposals:

  • Fit with CIT/ICES strategic focus.
  • Novel or cutting-edge nature of project.
  • Existing sources of funding for this type of project.
  • Potential of this seed project to enable government and/or industry support in future years.

An individual research project may receive a maximum of two years of grant support under this program, but normally the funding will be for one year. The student receiving the grant shall be designated the "Dowd ICES Fellow," and will be required to give a seminar to the university community on the results of the work.


PITA FISCAL YEAR 2002 AWARDS
Pennsylvania Infrastructure Technology Alliance (PITA) funding for Fiscal Year (FY) 2002 has been provided by the Commonwealth of Pennsylvania. PITA is a collaborative effort between ICES, the Center for Advanced Technology for Large Structural Systems (ATLSS) at Lehigh University and the PA Department of Community and Economic Development (DCED).

The mission of PITA is to increase the operating efficiency of PA companies and enhance economic development within the Commonwealth by: combining physical and informational infrastructure technology expertise; leveraging technology development in design, manufacturing, biomedical and environmental areas; focusing research and educational capabilities of two world-class universities on technology issues; linking companies and agencies with students and faculty to create high-paying jobs; and retention of highly educated students in the Commonwealth.

In July of this past year, ICES sent out a call for proposals for research, education and outreach projects. A large number of proposals were submitted. Unfortunately, not all proposals could be accepted because of funding limitations. The large number of proposals and ongoing attempts to share PITA opportunities with other educational institutions in Pennsylvania prevented us from providing as much funding as we would like. We, at ICES, thank those researchers who took the time to submit proposals and for their interest in ICES and the PITA program. We encourage principle investigators (PIs) and Co-PIs who did not receive FY 2002 PITA funding to keep in touch with ICES and its interdisciplinary research efforts and to submit new proposals later in 2002 for possible FY 2003 funding.

PITA Fiscal Year 2002 Awards - proposals that were awarded funding:

A Case Study in Modeling Organizational Structure and Operation: the American Red Cross in Pennsylvania
co-PIs: Kathleen Carley, SDS, EPP, Heinz; Jim Garrett, CEE; Louise Comfort, University of Pittsburgh

Computational Studies of Chemical Corrosion
PI: David Sholl, ChemE
co-PIs: Michael Widom, Physics; Hansong Cheng, Air Products and Chemicals, Inc.

Engineering Design Projects Course
co-PIs: Art Westerberg, ChemE; Cristina Amon, MechE & BioMedical and HealthE; Jim Garrett, CEE; Eswaran Subrahmanian, ICES; Annette Jacobson, ChemE; John Wesner, MechE

Investigation of the Thermal Stability of Metal-Oxide-Silicon Carbide Devices
PI: Lisa Porter, MSE
co-PI: Kristofer Roe, Silicon Power Corporation

Modeling & Simulation of Phonon Transfer in Nanotechnology
PI: Mehdi Asheghi, MechE
co-PIs: Cristina Amon, MechE & IBioMedical and HealthE; Myung S. Jhon, ChemE

Formulated Suftactant Systems: Molecular Self-Assembly and the Control of Interfacial Forces and Dynamics
co-PIs: Stephen Garoff, Physics; Dennis C. Prieve, ChemE; Robert D. Tilton, ChemE

Novel Numerical Algorithm Development in Computational Fluid Dynamics - An Optimized Particle-Grid Hybrid Approach
PI: Myung S. Jhon, ChemE
co-PIs: Larry T. Biegler, ChemE; Omar Ghattas, CEE

Exploring the Use of Commercial Wireless Platforms and Embeddable Sensors for Assessing Element Quality on Construction Sites
co-PIs: Jim Garrett, CEE; Burcu Akinci, CEE; Mark Patton, CEE

Exploring the Use of Speech-Control in Mobile IT Support for Field Engineers on Construction Sites
co-PIs: Jim Garrett, CEE; Asim Smailagic, ICES

A Robotically Guided Urological Endoscope with Integrated Micro Sensors
PI: Qiao Lin, MechE
co-PIs: Steven G. Docimo, University of Pittsburgh School of Medicine & Children's Hospital of Pittsburgh; Kaigham J. Gabriel, ECE & Robotics; Cameron Riviere, Robotics

Design and Decision Support for Water Infrastructure and Environmental Decision-Making
co-PIs: Scott Farrow, EPP & Heinz; Mitchell Small, CEE & EPP

An in situ MEMS Device for Detecting Cracks or Weld Failures in Steel
co-PIs: David Greve, ECE; Irving Oppenheim, CEE & Architecture

Collagen/Polymer Systems for Tissue-Engineered Nerve Guides
PI: Kacey Marra, ICES
co-PIs: John Doctor, Duquesne University Biology

MEMS Transducers for Acoustic Emission Testing of Structural Materials
PI: Irving Oppenheim, CEE & Architecture
co-PI: David Greve, ECE

EPIS: Engineering Process Information Systems
PI: Eswaran Subrahmanian, ICES
co-PIs: Art Westerberg, ChemE; Christopher Lee, ICES; Bob DiSilvestro, Bombardier Total Transit Systems; Curtis McCullers, Bombardier Total Transit Systems; Ron Anthony, Bombardier Total Transit Systems

Managing Product Variety by Managing Workflow and Engineering Change
PI: Eswaran Subrahmanian, ICES
co-PIs: Art Westerberg, ChemE; Christopher Lee, ICES; Judith Spering, Boeing

Gaining Control Over Angiogenesis in Tissue Engineering Bone Contructs
PI: Phil Campbell, ICES
co-PIs: Lee Weiss, Robotics; Janine Orban, ICES ; John Doctor, Duquesne University Biology; Larry Schultz, Robotics

Implantable, Telemetry-Based MEMS Bone Sensor
co-PIs: Phil Campbell, ICES; Gary Fedder, ECE & Robotics; Mark Carl Miller, Duquesne University Health Sciences; Lee Weiss, Robotics

Uniform Coating of Microparticles for Controlled Drug Delivery
PI: Kacey Marra, ICES
co-PI: Lynn Walker, ChemE

Program Analysis for the Reliability of Information Systems (Year 2)
PI: Pradeep Khosla, ECE
co-PI: Michael Bigrigg, ICES

Technology Enhanced Team Based Design: Collaboration Across Time and Space Using a Pervasive Computing Infrastructure
co-PIs: Asim Smailagic, ICES; Dan Siewiorek, HCII & CS & ECE; Alex Hills, EPP & CS; Michael Gabrin, Vocollect; Bob DiSilvestro, Bombardier Total Transit Systems; Harold Hall, Hall Industries; Panos Chrysanthis, University of Pittsburgh CS

Object Oriented Application Development in CAD
PI: Ulrich Flemming, Architecture

Augmented Manufacturing Using a Context Aware Computing Infrastructure
co-PIs: Asim Smailagic, ICES; Dan Siewiorek, HCII & CS & ECE; Marvin Sirbu, EPP & GSIA; Chuck Brandt, Pittsburgh Digital Greenhouse; Bob DiSilvestro, Bombardier Total Transit Systems; Harold Hall, Hall Industries; Panos Chrysanthis, University of Pittsburgh CS

Machine-Learning Based Tool Development for Thermal Design of Electronics Enclosures
PI: Thomas Stahovich, MechE
co-PI: Cristina Amon, MechE & BioMedical and HealthE

A Cost Effective Computer-Aided Orthopedic Surgery
PI: Lee Weiss, Robotics
co-PIs: Kenji Shimada, MechE; Gennady Neplotnik, ICES; Raju Patil, Robotics; Tomotake Furuhata, MechE; Norman Krause, Shadyside Hospital; Robert Mendicino, West Penn Hospital

Design, Construction and Path Planning for Mechatronic Demining
PI: Howie Choset, MechE & Robotics

Stochastic Modeling and Simulation in Design
PI: Chris Paredis, ICES
co-PIs: Kemal Sahin, CEE; Urmila Diwekar, CEE

New Course: Modeling and Simulation in Systems Engineering
PI: Chris Paredis, ICES

Product Models to Support Design Interation
PI: Chris Paredis, ICES
co-PIs: Li Han, ICES

Rapid Prototyping Education at CMU
co-PIs: Susan Finger, CEE
Chris Paredis, ICES

Medical Body Monitors Re-Purposed for Context Aware Computing Applications
PI: Asim Smailagic, ICES
co-PI: Francine Gemperle, ICES

ICES/PITA Education & Outreach
co-PIs: Cristina Amon, MechE & ICES & BioMedical and Health; Susan Finger, CEE; Annette Jacobson, ChemE; Chris Paredis, ICES; Kacey Marra, ICES; Rhonda Moyer, ICES; Dana Hilinski, ICES

Design Problem Formulation Course (An International Experiment)
PI: Eswaran Subrahmanian, ICES
co-PIs: Art Westerberg, ChemE; Sarosh Talukdar, ECE

Assessment of Rupture Potential of Abdominal Aortic Aneurysms by Computational Modeling and Simulation
PI: Amy Kennedy, Biological Sciences
co-PI: Ender Finol, ICES; David Vorp, University of Pittsburgh, Surgery

Free-Form Surface Design for Sheet-Metal Components
co-PIs: Kenji Shimada, MechE; Miguel Vieira, Computer Integrated Engineering Lab; Tomotake Furuhata, Visiting Scientist, IBM Japan; Jack Beuth, MechE

Multi-Scale Processing and Mechanics of Next Generation Steel Coatings
co-PIs: Jack Beuth, MechE; Sridhar Setharaman, MSE

Wireless Sensors Embedded in Composite Structures
co-PIs: Mark Patton, CEE; Joachim Grenestadt, Lehigh


UPDATE: ICES STRATEGIC PLAN
ICES is undertaking a strategic planning initiative to better serve our members and Carnegie Mellon University.

Hard work and dedication by our members have enabled significant growth and diversification. But factors including a slowing economy, changing university priorities, and changing priorities for federal, state and industrial research funding makes the development of a new strategic plan a necessity.

Informal meetings were held in September, November and December to determine how comprehensive the strategic planning effort should be, to collect background data, to identify benchmarks and discuss the most effective ways to involve laboratory directors, and research faculty in the process. A preliminary situational analysis was conducted. Then, a set of questions was provided to laboratory directors in late November/early December to identify critical issues or concerns for a preliminary strengths, weaknesses (SW)/opportunities, challenges (OC) analysis. The situational analysis and SW/OC analysis indicate that ICES is in a good strategic position (i.e., more strengths and opportunities than weaknesses and challenges) to respond to stresses from our internal and external environments.

Formal planning meetings will be held in late January to determine the direction that ICES should take over the next 3 to 5 years. While a single meeting is the preferred means of reaching everyone, scheduling conflicts made the selection of a single date very difficult. ICES faculty members are encouraged to attend as many meetings as possible. Focus groups will be developed to work on inputting goals, metrics and plan implementation. Additional meetings may be held in February as the plan develops.

The strategic planning initiative is a process and its success depends on member involvement. Laboratory directors and research faculty have a significant role to play in the future success and vitality of ICES. Please get involved!


NEW CARD READER SYSTEM IN HAMBURG HALL
Beginning on Monday February 4, Hamburg Hall will have a new card reader access. This is an effort to improve security in the building during off-hours. Access to the building during the restricted hours listed below will require a current Carnegie Mellon student, faculty or staff I.D. card.

Restricted Access Hours
Monday through Friday - 10pm to 6am
Saturday - before 6am and after 6am
Sunday - all day

OPERATION
Card entry to the building during restricted hours will be allowed ONLY through the DOUBLE DOORS in the rear of the building. The revolving front door and all other doors will be locked during these hours.

TESTING
If your Carnegie Mellon ID card has a magnetic stripe on the back and is currently valid, it should work in this system. If you do not have an ID card, go to the HUB located basement of Warner Hall to obtain one. During the week of January 28 the system will be activated without locking the doors so that you may test your ID card. You may also test your card on the active system in Newell-Simon Hall.

PROBLEMS
1. Card doesn't work? Go to the HUB to get a new card.
2. Having difficulty gaining access? Call Security at 8-6232 for access to the building.
3. Holding a special event requiring non-authorized individuals to gain access during restricted hours? Contact Security at 8-6232.
4. Having more systematic problems? Contact your department administrator.

HINTS/CAUTIONS
1. After swiping the card, pull the door open or activate the handicapped system within 5 second. The lock activates again immediately upon opening so "jiggling" the doors will re-lock them.
2. Do not give strangers access to the building if you see someone trying to get inside the door. Even though it seems to be the polite thing to do, it reduces the effectiveness of this security system.
3. DO NOT PROP THE DOORS OPEN UNDER ANY CIRCUMSTANCES. An alarm will sound if the door stays open for more than 30 seconds and security will come to investigate.


GENESIS BABY DRIVE
This past December, the second annual baby item drive for the Genesis House took place on campus. Genesis would like to thank everyone who donated items. Kacey Marra, ICES faculty, organized the drive and transported all of the donations to the Washington branch of the Genesis House. Kacey would also like to thank everyone who contributed, and give a special thanks to Rhonda Moyer for passing on the announcement to other business managers on campus.



HONORS & AWARDS

Rhonda Moyer, Administrative & Financial Manager, ICES
The College of Engineering has elected Rhonda Moyer as the first recipient of the Burritt Education Award. This award was recently founded in memorandum of Timothy J. Burritt, former undergraduate advisor for the College of Engineering to recognize CIT staff members who successfully maintain a balance of work and schooling.

Rhonda was chosen for the award based on her perseverance in continuing education while exhibiting exemplary professional performance. This past May, Rhonda received a masters degree in Public Management from Carnegie Mellon's Heinz School. Dean Anderson made the official announcement at the annual CIT Staff Recognition Awards Ceremony on January 8th.


Raj Sinha, Post Doc, ECE, ICES
Congratulations to Raj Sinha who recently received his Ph.D. in Electromechanical Systems Design. The title of his thesis was "Compositional Design and Simulation of Engineered Systems". Raj will continue his job at IC Mechanics, a MEMS company and Carnegie Mellon start-up located in Pittsburgh.


Art Westerberg, ChE, ICES
Art Westerberg was elected the first recipient of the Distinguished Professor of Engineering Award from the College of Engineering, based on his accomplishments and lifelong contributions in system engineering and multi-disciplinary design research and education. This newly established award was presented at the first CIT Awards Banquet along with the ICES Fenves Award on January 26, 2002 at the Pittsburgh Athletic Association.



IN THE SPOTLIGHT

Helen Granger
Helen Granger, a user-interface designer and researcher for the n-dim group has resigned from her position at ICES. After spending five years at Carnegie Mellon focusing mainly on graphic arts production and design, Granger has decided to leave the university to pursue new interests and concentrate solely on art and illustration. She is looking forward to exploring new areas of creativity and expression. Helen can be contacted via email at hgranger@hgranger.com. To view her portfolio, visit her website at www.hgranger.com.

Farewell and good luck, Helen!


NANOSCALE HEAT-TRANSFER PROJECT

Phonon Transport in Nanostructures with Applications to Ultra-Thin Silicon-On-Insulator (SOI) Transisters
Funding: NSF - Nanoscalse Interdisciplinary Research Team (NIRT), IBM and PITA


A Schematic of a Field
Effect Transistor (FET)
made on a SOI

Advances in microfabrication processes have led to a continuous miniaturization of microelectronic and data storage devices as well as MicroElectroMechanical Systems (MEMS) (e.g., mechanical and chemical sensors) that contain semiconductor or metallic layers only a few nanometers thick. The performance and reliability of microelectronic and data storage devices (systems) are influenced by transport of thermal energy in multilayer structures. Because the thermal phenomena are not directly responsible for the electrical or optical functionality of these devices, they often receive only indirect consideration during system design. The situation is however changing rapidly as dimensions of these devices approach several nanometers and timescales of their operation gets closer to the nano- to pico-seconds range. Silicon-on-insulator circuits promise advantages in speed and processing cost compared to circuits made from bulk silicon. Around the year 2000, IBM built and tested SOI-based microprocessors that have 20 to 25% faster circuit speed compared to CMOS technology made on bulk silicon substrates (See figure). The source of increased SOI performance is the elimination of area junction capacitance and the "body effect" in bulk CMOS technology. However, the buried silicon-dioxide layer in SOI circuits has a very low thermal conductivity (~1 W m-1 K-1) compared to the silicon device layer. This results in a relatively large thermal resistance between the device and the chip packaging. The thermal conduction or phonon transport in the silicon device layer strongly influences the peak temperature rise in SOI devices.

Recently, a multidisciplinary faculty, research associates and students from the Institute for Complex Engineered Systems (ICES), Mechanical, Electrical and Computer, and Chemical Engineering Departments have received a $1,300,000 funding from National Science Foundation (NSF), and funding from the Pennsylvania Infrastructure Technology Alliance (PITA) to investigate in collaboration with IBM the "Phonon Transport in Nanostructures with Application to Ultra-Thin Silicon-On-Insulator (SOI) Transistors." This project focuses on the study of two major nanoscale phenomena: (a) phonon transport in single crystal silicon layer of thickness in the range of 10-50 nm and (b) ballistic phonon transport near hotspots (~10 nm) in the active region of silicon-on-insulator (SOI) transistors. The experimental part of the study involves the very first measurements of thermal conductivity of nanometer size, single crystal silicon layer and ballistic phonon transport near a hotspot in a transistor. The computational effort will focus on numerical simulations of phonon Boltzmann transport equation (BTE) in the relaxation time approximation, accounting for phonon dispersion as well as frequency dependent phonon mean free paths in silicon.

Researchers for the project include: Mehdi Asheghi, faculty, ME; Cristina H. Amon, faculty ME & director ICES; Gary K. Fedder, faculty, ECE; Myung S. Jhon, faculty, ChE; Jayathi Murthy, faculty, Purdue; and Shi-Chune Yao, faculty, ME. Student researchers: Mohamad S. Sadeghipour, Carlos Gomes, Sreekant Narumanchi, Yizhang Yang, Bahareh Behkam, Sartaj Ghai, Keivan Yazdani, Shahab Shojaeizadeh, Sartaj Ghai, Wenjun Liu and Shu Zhang


BIOMEDICAL ENGINEERING AT ICES
ICES is a significant contributor to biomedical and health engineering research and education at CMU. ICES is currently supporting six biomedical engineering projects in 2002. These projects leverage CMU competencies in bone-tissue engineering, robotics, information technology and microelectromechanical systems (MEMS). Biomedical engineering projects include: robotically guided endoscopes; tissue engineered nerve guides; angiogenesis in tissue engineering bone constructs; implantable telemetry based MEMS bone sensors; coating of microparticles for controlled drug delivery; computer-aided orthopedic surgery and context aware computing in medical body monitors.

Robotically Guided Endoscopes
Robotically guided endoscopes promise to overcome these drawbacks of existing urological endoscopes. This research project is a collaborative effort between Carnegie Mellon University and the Children's Hospital of Pittsburgh. The tip of a robotic endoscope is equipped with sensors that are capable of identifying the lumen of the urethra or the ureter. Using this sensory feedback (instead of limited visual information) the endoscope tip can be continuously adjusted to point in the direction of the lumen. The endoscope can, therefore be advanced faster, causing less discomfort and a reducing the potential for tissue injuries associated with endoscopic procedures.

Tissue Engineered Nerve Guides
ICES researchers are pursuing new strategies to repair nerve injuries, such as spinal cord injury. This research involves seeding biodegradable scaffolds with donor cells and growth factors, in this case a nerve guide, then implanting the tubes to induce and direct the growth of new, healthy nerve tissue. If successful, this technology will replace existing treatments for peripheral nerve regeneration including autograft as well as surgical realignment of the severed ends.

Angiogenesis in Tissue Engineering Bone Constructs
ICES is also evaluating techniques for implanting biodegradable scaffolds seeded with cells and/or signaling molecules into bone defect sites to induce and direct the growth of new healthy bone. Cells that are delivered with the scaffolds to the defect sites or cells that migrate into the implanted scaffolds from surrounding healthy tissue need timely access to a vascular supply. This research is exploring new ways to create vasculature within scaffolds and defects (angiogenesis) in a timely, organized, and safe fashion.

Implantable Telemetry Based MEMS Bone Sensors
Research is also being conducted on bone sensors to detect in vivo bone stress via a wireless RF interface. The sensor is envisioned to be a 2mm by 2 mm by 300mm silicon CMOS chip with no external wires. Such a size is minimally invasive, as it is smaller than typical screws used in setting bone fractures. Stress is detected using embedded piezoresistive strain gages made from the CMOS gate polysilicon layer. The chip surface will be textured with appropriate feature sizing to optimize attachment of bone tissue. Several kinds of texture will be explored including parallel ridges, dimpled surfaces and pimpled surfaces, all with varying micron-scale pitch and depth of the features. Chips will be covered with a titanium outer layer for biocompatibility. An initial set of experiments to verify biocompatibility and to measure tissue adherence will be performed by implanting samples in lab rats. The long-term goal is to integrate implantable bone sensors with companion development of a tetherless RF interface, which transmits the stress information and receives power from an external RF source.

Computer-aided Orthopedic Surgery
ICES researchers are also pioneering Computer-Aided-Surgery (CAS) techniques. CAS techniques are emerging methodologies that help surgeons improve outcomes of their procedures by allowing them to optimally preplan surgical procedures in a virtual environment. CAS further allows them to precisely execute their plans during the actual surgery. While CAS is applicable to a broad range of surgical specialties, CAS is particularly well suited to facilitating and improving the outcomes of osteotomy procedures for orthopedic surgery. These procedures are used to reshape a deformed or malaligned bone by cutting the bone so that the remaining mobile segments can be manipulated into the desired shape. This is accomplished with the aid of fixation devices to temporarily stabilize the bone until new bone grows into and across the osteotomy site.

Coating of Microparticles for Controlled Drug Delivery
The localized delivery of growth factors and drugs is important in biomedical applications, in particular for tissue engineering. ICES researchers are, therefore, working to coat biodegradable polymer microspheres with a protective membrane which then allows the drug-containing microspheres to become embedded in tissue-engineered scaffolds.

Context Aware Computing in Medical Body Monitors
ICES researchers are working collaboratively with Body Media to apply context aware computing concepts developed in the Laboratory for Interactive Computing (LINCS) to their medical body monitor. Researchers envision tapping into the sensing power of Body Media's product and applying it to create parameters for understanding a user's computing context. Understanding a users state (i.e., if the user is stressed, nervous, busy or tired) leads to the development of treatments or therapies that meet the unique needs associated with each emotional state.

Simulation-Based Design of Artificial Organs
A major challenge in the field of artificial organ development is understanding the behavior of blood flow. ICES researchers in partnership with researchers from the University of Pittsburgh Medical Center (UPMC) - McGowan Center for Artificial Organ Development, Texas A&M and the University of Washington are working on a project to develop multiscale models of blood flow. Blood flow models will resolve the behavior of blood in complex geometries - from the organ level to the blood cell level. These models will form the basis for simulation-based, next-generation artificial organ design.

The initial project emphasis is on blood flow and artificial heart devices, but algorithms and Lagrangian computational methods developed as a result of this research will provide insight into many other diseases including hypertension, atherosclerosis and thrombosis, sickle cell anemia and stroke.

This multidisciplinary project brings together mathematicians, biochemists, bioengineers, computational fluid dynamicists, computer scientists, hemorheologists, numerical analysts and transplant surgeons and combines Carnegie Mellon University's leadership in interdisciplinary computer/computational sciences with UPMC's world class programs in biological sciences and transplant surgery.

Artificial Lungs
ICES is currently conducting an artificial lung optimization project in collaboration with the Artificial Lung Program and Department of Surgery at UPMC. ICES researchers are performing mathematical modeling, large-scale numerical simulations and predictions as well as some component prototyping whereas researchers at UPMC carry out the in-vitro and animal experimentation. Numerical predictions and optimization enables the development of superior Intravenous Membrane Oxygenator (IMO) devices, known by the lay public as artificial lungs.

The goal of this research is to develop a simulation-based methodology for artificial lung and blood-wetted organ design. The project requires the creation of mathematical models, computational tools and validation by in-vitro experimentation. If successful, optimal design methodologies will lead to the design of artificial organs with improved gas exchange capability, minimal risk of blood trauma and thrombosis. The objective of this research project is to develop methods of improving artificial organ function, greatly improving a recipient's quality of life.

Aortic Aneurysms
Abdominal Aortic Aneurysms (AAAs) are localized balloon-shaped expansions commonly found in the infrarenal segment of the abdominal aorta, between the renal arteries and the iliac bifurcation. Abdominal aortic aneurysm rupture is the 15th leading cause of death in the United States, affecting patients over 55 years of age, typically 2-4% of elderly males. Typical treatment consisting of conservative or surgical management is based on the surgeon's estimation of the risk of rupture vs. mortality and morbidity during surgery combined with the patient's life expectancy. Aneurysm size is often used as the primary indicator of potential rupture by measuring the AAA's maximum diameter. Elective Surgical resection is justified when this diameter exceeds the critical value of 5 cm. It is well known, however, that not all large aneurysms rupture and that aneurysms with a maximum diameter less than the critical value may. Therefore, the criterion results unreliable for the individual patient and there is need for a better assessment of rupture potential.

ICES is assessing the rupture potential of AAA's using computational modeling and simulation, which uses large-scale numerical simulations and modeling based on physiologically realistic measurement obtained during patient diagnosis. The objective of this research is to develop a non-invasive technique for the assessment of aneurysm rupture by integrating the mechanical properties of the artery wall and physiologic blood flow conditions into a unique computational model of aneurysm hemodynamics. This research is being performed in collaboration with Vascular Surgery and Vascular Biomechanics Research Lab of the Section of Vascular Surgery.



ICES EVENTS

ANNUAL ICES HOLIDAY PARTY -- See Event Photos --
The ICES Holiday Party 2001 took place on December 12 at the
University Club in Oakland. The evening included dinner, dancing, and karaoke. See attached photos for a peak at the festivities.

PITA SYMPOSIUM 2002 -- Symposium agenda --
Mark your calendars for this year's PITA Symposium which will be held on Monday, March 25, at the Harrisburg Hilton & Towers in Harrisburg, Pennsylvania. Brochures will be distributed in the coming weeks, as well as, information regarding posters for the symposium. For more information, please contact Rich Hoff at rhoff@andrew.cmu.edu.

ICES SEMINARS
Please mark your calendars for the following seminars at ICES and at Mechanical Engineering. More information will be available in the coming weeks.

February 15, at 12:15pm in room 1202 Hamburg Hall, Dusan N. Trivic, Research Fellow, ICES, will speak on "Modeling of radiation: trends, new results and applications." -- Go to Bio and Abstract

March 1, at 2:30pm in room 125 Scaife Hall, Katya Hanson of Bell Labs will speak on "Systems Engineering."

March 15, at 2:30pm in room 125 Scaife Hall, Amy Fleischer of Villanova will speak on "Thermal Management of Electronics."



ICES NEWSMAKERS

IEEE Transactions on VLSI Systems Special Issue on Systems Level Design -
December 2001,
Asim Smailagic is guest editor for this issue.
http://www.ieee.org/organizations/pubs/transactions/tvlsi.htm

TEQ Magazine
November 2001,
Kacey Marra is quoted on tissue engineering research at ICES.
PDF of article

IEEE Transactions on Mobile Computing
Asim Smailagic has been appointed Associate Editor of the new journal for the 2002-2004 term.
http://www.computer.org/tmc/index.htm

Frankfurter Allgemeine Zeitung
March 25, 2001,
Christian Buergy quoted on wearable computer project with Bosch.
PDF of article

iNews Production Staff

Tiffany Booth, Staff Writer, tbooth@andrw.cmu.edu
Dana Hilinski, Editor, hilinski@andrew.cmu.edu
Donna Yocum, Webmaster, donnay@andrew.cmu.edu

iNews is a bimonthly newsletter designed to serve the ICES community. All faculty, staff and students are encouraged to email any submissions, questions or comments they may have to any of the iNews staff members.